Nano Interactive Brings Intent Intelligence to Index Exchange’s Index Cloud

by ExchangeWire PressBox on 15th Oct 2026 in News

Nano Interactive, the signal intelligence platform, today (15th October, 2026) shared initial performance evidence from the deployment of its containerised RTB solution on Index Exchange’s Index Cloud. Nano is one of the first to run decisioning logic natively inside the auction infrastructure of a major exchange, pulling a decade of experience in multi-signal intelligence directly into the bid-stream.

For advertisers, agency trading desks, and SSPs, the integration enables real-time audience matching closer to the origin of the impression. This brings the clarity of Nano’s intent-based audience reach together with the sophistication of in-bid-stream media buying, resulting in more intelligent media investment for advertisers and increased campaign performance.

The problem with downstream enrichment

With traditional data enrichment, audience or contextual signals are added to a bid request after it has left the publisher. That signal has to travel from the enrichment layer to the decisioning layer before it can be used, and that trip adds latency. Nano's containerised model removes the trip entirely, with the signal being applied closer to the origin of the impression, inside the same auction, with no travel time.

Index Cloud’s architecture is designed to reduce latency by processing at the edge of the impression, enabling applications or solutions to enact a decision within the initial 5ms before an impression becomes visible in the bid-stream. For Nano, this is the natural home for intent intelligence, and for agencies and SSP partners, it is the difference between real-time intent meeting a real-time auction, versus a signal that has aged by the time it is used.

As Carl White, chief executive officer at Nano Interactive, explains: "Intent has a half-life measured in milliseconds. The further a signal travels from the moment it is generated, the less effective it becomes. Index Cloud lets us close that distance entirely by applying our decade of intelligence to live campaigns. We’re not appending data to a bid request after the fact - we’re live inside the auction, at the source of the signal, in the moment it matters."

White continues: "The containerised model is more cost-effective, faster, and it sees the full bid-stream. The challenge is making an intent engine work inside an external box with a fixed compute and no direct network. We fit almost a hundred million classified webpages, millions of CTV titles, and a KPI-optimised ML model into one container that makes decisions in less than 5 milliseconds. What excites us most is using more signals closer to where they originate for decisioning and applying Nano's proprietary ML models to improve outcomes."

"Nano's containerised intent signal shows what's possible when signal and decisioning sit in the same place at the same time," said Paul Zovighian, VP of marketplaces at Index Exchange. "Index Cloud is built to bring more of that kind of intelligence into the auction, closer to the impression, without changing how our partners transact today. Partners like Nano get a faster, more direct path to the decisions they're already making."

The benefits for agency partners and buyers

• Performance uplifts from live intent. Early testing showed a 30%+ CTR uplift for campaigns using Nano’s containerised intent signal, versus conventional enrichment. Capturing intent at the point of transaction gives buyers a higher-fidelity signal.

• Increased relevancy. Richer multi-signals inside Index’s own infrastructure move decision-making to the sell-side, with the audience creator. Reach becomes more relevant, improving performance for the same budget.

• No change to existing trading workflows. Nano operates within the auction, so agencies transact through Index Exchange exactly as today. It also follows the new IAB Tech Lab Agentic Real-Time Framework (Index Exchange is a founding contributor): one API, built once, for any compliant exchange.

• Custom signal intelligence via NanoQ (Agentic Media Planner). Trading desks can define, build and activate custom intent-based audiences directly through Index. With that signal running at the edge of the impression, agencies get purpose-built precision with real-time performance.

Nano’s container is live today on Index Cloud.